E Vitamin Synthetic Source Drug Information [ H.J. Sutton Industries ]
Table of content
E Vitamin Synthetic Source category:
Active ingredients:
E Vitamin Synthetic Source companies and manufacturers:
General Information
E Vitamin Synthetic Source forms, composition and dosages:
- Capsule; Oral; Vitamin E (DL-Alpha Tocopherol Acetate) 200 units
- Capsule; Oral; Vitamin E (DL-Alpha Tocopherol Acetate) 400 units
- Capsule; Oral; Vitamin E (DL-Alpha Tocopherol Acetate) 800 units
Indications, usages and classification codes:
- A11AA03 - Multivitamins and other Minerals including combinations
There is an additional general information about this medication active ingredient vitamin e (tocopherol acetate, tocopherol palmitate or other related chemical compounds):
Pharmacological action
Tocopherol (vitamin e) has an antioxidant effect, is involved in the biosynthesis of heme and proteins, cell proliferation, tissue respiration, and other critical processes of tissue metabolism, prevents hemolysis of red blood cells, prevents increased permeability and capillary fragility. This medication fills a shortage of vitamin E. Inhibits free radical reactions, prevents the formation of peroxides that damage cellular and subcellular membranes. Stimulates the synthesis of heme and heme containing enzymes - hemoglobin, myoglobin, cytochromes, catalase and peroxidase. Improves tissue respiration, stimulates the synthesis of proteins (collagen, enzymes, structural and contractile proteins of skeletal and smooth muscle, the myocardium), protects against oxidation of vitamin A. Inhibits the oxidation of unsaturated fatty acids and selenium (a component of microsomal electron transport system). Inhibits the synthesis of cholesterol. From the gastrointestinal tract is slowly absorbed about 50%, the highest level in the blood after 4 hours for absorption requires bile acids. In the process of absorption forms a complex with lipoproteins, which are intracellular carriers of vitamin E. Comes mainly in the lymph, then - in the general circulation, where it binds primarily to alpha-1 and beta-lipoprotein, in part - to serum albumin. When metabolic protein transport is difficult. Deposited in the adrenal glands, pituitary, testes, fat and muscle tissue, erythrocytes and liver. Undergoes metabolism and is excreted from the body (in unmodified form and as metabolites) in bile (90%) and urine (about 6%).Pharmacokinetics
If ingestion absorption of 50% during suction forms a complex with lipoproteins (intracellular carriers of tocopherol). For absorption requires bile acids. Associated with alpha1- and beta-lipoprotein, in part - to serum albumin. When metabolic disorders a protein transport is difficult. Cmax is reached after 4 h. Deposited in the adrenal glands, pituitary, testes, fat and muscle tissue, erythrocytes and liver. More than 90% is excreted in bile, 6% - the kidneys.Why is E Vitamin Synthetic Source prescribed?
Vitamin deficiencies, conditions of convalescence after a disease occurring with a feverish syndrome, high physical activity, older age, disease ligamentous system and muscles. Climacteric autonomic disorders. Neurasthenia with fatigue, asthenia neurasthenic syndrome, primary muscular dystrophy, posttraumatic, postinfectious secondary myopathy. Degenerative and proliferative changes in the joints and ligamentous apparatus spine and large joints.Dosage and administration
Usually prescribed to 100-300 mg / day. If necessary the dose may be increased to 1 g / day.E Vitamin Synthetic Source side effects
Possible: an allergic reaction, with a reception in high doses - diarrhea, epigastric pain, when IM injection - pain, infiltration at the injection site.Contraindications
Increased sensitivity to tocopherol.Using during pregnancy and breastfeeding
Tocopherol is used during pregnancy and lactation (breastfeeding) when indicated.Special instructions
With caution tocopherol should be used in severe cardiosclerosis, myocardial infarction, with an increased risk of venous thromboembolism.E Vitamin Synthetic Source drug interactions
In an application with tocopherol may change the effects of warfarin and dicoumarol.There are reports of reduced effectiveness of simultaneous treatment with iron for children.
With the simultaneous application of tocopherol with cyclosporine increased absorption of cyclosporine.
E Vitamin Synthetic Source in case of emergency / overdose
Symptoms: creatinuria, diarrhea, epigastric pain, decreased capacity for work.PLEASE, BE CAREFUL!
Be sure to consult your doctor before taking any medication!
- E-Drops Ranbaxy
- Embial Merck
- E-Mil Fontovit Laboratorios
- Ephynal Roche; Bayer Schering Pharma; Institute of Pharmaceutical Research and Technology
- Eternal Roche; Bayer Schering Pharma
- Eusovit Strathmann
- E-Vimin AstraZeneca
- Eviol GA Pharmaceuticals
- Evion Merck; Bracco
- E-Vit Istituto Biochimico Pavese Pharma
- Evitina C.T. Laboratorio Farmaceutico
- Ixopolet Best Laboratorios
- Mega E Mayne Pharma
- Novo E Novopharm
- Novo E DL Synthetic Novopharm
- One A Day with Non-Medicinal Garlic Bayer Schering Pharma
- Oxivite J. Neves Laboratorio
- Plusvital-E Plusvital Ireland
- Poly-Tonine E Vetoquinol
- Sanavitan S Bottger
- Acti-Copherols Acti-Form
- Acti-D Alphacopherol Acti-Form
- Acti-Succinate Acti-Form
- Advanced E with Non-Medicinal Grape Seed Extract Vita Health Products
- AFI-E Nycomed
- Alfa-Tocopherol Belmedpreparaty
- Alfa-Tocopherol Bryntsalov-A
- Alfa-Tocopherol Lumi
- Alfa-Tocopherol Nizhpharm
- Alfa-Tocopherol Pharmstandard-Marbiopharm; Biotec MFPDK
- Alfa-Tocopherol Shchelkovo Vitamin Plant
- Allsan Vitamin E Biomed, Switzerland
- Alpha Keri Silky Smooth Bristol-Myers Squibb
- Amino-Opti-E Tyson Nutraceuticals
- Antioxidans E Hevert-Arzneimittel
- Apozema Vitamin E Apomedica
- Aquasol E Sanofi-Aventis; Columbia Laboratories; Mayne Pharma
- Aquasol E TPGS Columbia Laboratories
- Aquavit-E Cypress Pharmaceutical
- Auxina E Chiesi